How does 3,4-dihydroxybenzoic acid achieve its antioxidant effect?

3,4-dihydroxybenzoic acid has many functions, such as antioxidant, anti-inflammatory, anti-hyperglycemia and so on. So, does anyone know about its function mechanism? Today, let’s talk about the antioxidant effects of 3,4-dihydroxybenzoic acid.

How does 3,4-dihydroxybenzoic acid achieve its antioxidant effect? Ginger, 3,4-dihydroxybenzoic acid, can reduce the cell survival rate induced by hydrogen peroxide in vitro, prevent oxidative damage, help relieve oxidative stress in vivo, resist the activity of peroxidase and inhibit the generation of free radicals, so as to play a certain protective role. The oxidative damage of hepatocytes induced by T-BHP can be protected by hibiscus 3,4-dihydroxybenzoic acid.

In animal experiments, 3,4-dihydroxybenzoic acid has protective effects on oxidative and histopathological damage of heart tissue induced by dioxins. 3,4-dihydroxybenzoic acid can increase the thiobarbituric acid active substances in the heart tissue, and reduce the content of catalase, glutathione, glutathione peroxidase and superoxide dismutase, so as to reduce the bleeding and even necrosis of the heart tissue.

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