4-vinylphenol, also known as p-vinylphenol, is a monomer used in the synthesis of various polymers, such as polyvinylphenol, polyvinyl alcohol, and copolymers with other monomers such as acrylates and vinyl acetate.In the pharmaceutical industry, 4-vinylphenol has several applications, including:
Polyvinylphenol (PVP) coatings: PVP is used as a coating material for oral solid dosage forms, such as tablets and capsules, to improve the stability and protect the active ingredients from moisture and air.
Polyvinyl alcohol (PVA) in drug delivery systems: PVA is used as a matrix former in the preparation of controlled-release drug delivery systems, such as films, hydrogels, and microspheres.
Copolymers in drug delivery systems: 4-vinylphenol can be copolymerized with other monomers, such as acrylates, to form copolymers that can be used in the preparation of drug delivery systems.These copolymers can improve the drug release characteristics and the mechanical properties of the delivery systems.
Polyvinylphenol as a dispersant: PVP can be used as a dispersant in the preparation of suspensions and emulsions.It helps to stabilize the suspensions and emulsions and prevent the aggregation of particles.
It’s important to note that the use of 4-vinylphenol in pharmaceuticals requires regulatory approval and must meet relevant quality and safety standards.