Nicotinamide is a white crystalline powder, odorless, bitter taste, and easily soluble in water, ethanol, and glycerol, hygroscopicity is weak, under the microscope, nicotinamide can show spherical particles, good fluidity, not agglomerate, nicotinamide is also naturally present in animals, plants.
Although best known for whitening, nicotinamide is extremely versatile. When nicotinamide enters the skin, it will be converted into a coenzyme to promote the generation of keratinocytes, thereby replacing the old keratinocytes on the skin surface. At the same time, nicotinamide can accelerate the synthesis of intercellular lipids, improve the skin’s moisture retention ability, and enhance the skin barrier from the inside out. It is well known that nicotinamide can whiten skin, but not everyone knows how it works. Nicotinamide can achieve whitening effects by blocking melanin transport to the skin surface and accelerating the shedding of aging keratinocytes. Nicotinamide is also one of the immunomodulators commonly used by dermatologists to eliminate inflammation in acne.
According to clinical studies, 2% nicotinamide can effectively control oil secretion, and 4% nicotinamide gel and 1% clindamycin treatment of acne effect are similar.
Nicotinamide is also widely used in anti-aging products because it promotes the synthesis of keratinocytes in the epidermis, which can reduce dryness, fine lines, and discoloration on the face.