In our bodies, there is the 25-Hydroxy Calcifediol substance, a form of vitamin B3, which is converted to vitamin D3 when the 7-dehydrocholesterol in our skin is exposed to the sun’s ultraviolet rays and converted to 25-hydroxy Calcifediol in the liver, The Calcifediol is then converted in the kidneys to 1, 25-dihydroxyvitamin D3, the active form of vitamin D3, and the 25-hydroxy Calcifediol is stored in the circulation.
The 25-hydroxy Calcifediol is essential to our health, growth and development and is related to a variety of diseases. The lack of 25-hydroxy Calcifediol causes absorption of calcium and phosphorus, affecting the normal development of bones and teeth. The situation is serious still can cause children rickets or adult rickets. It is recommended to take vitamin D daily and in moderate amounts, through sun exposure, diet, and in severe cases, supplements.