What effect can nicotinamide exert to melanin?

Nicotinamide is commonly used in the treatment of skin and various skin care products. Medical grade nicotinamide is mainly used in medical treatment, while cosmetic nicotinamide is used in skin care products such as moisturizing lotion, repair cream, essence, sunscreen, and face cream. It is a relatively safe ingredient with a small dosage and low cost, and it has various excellent performances, such as whitening, maintaining and diluting pigmentation, brightening skin tone, delaying aging, removing acne Anti-wrinkle, etc. the problems it can solve almost include our daily needs.

From the whitening effect, we gradually understand nicotinamide, which also makes us pay attention to it. Our skin color is closely related to melanin, erythroid, carotenoid, and other substances, especially melanin, which plays a key role. The content and distribution of melanin have a great impact on skin color. The more melanin, the darker the skin color. However, nicotinamide can inhibit the production of melanin and activate cyclic 3,5 nucleotide phosphodiesterase, an enzyme that can stimulate the decomposition of 3,5-cyclic adenylate in melanocytic hormones, Thereby inhibiting melanin production. Nicotinamide can not only inhibit the production of melanin but also reduce the melanin already produced.

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