The whitening mechanism of nicotinamide mainly plays a role in three aspects: accelerating the metabolism of aging keratinocytes, inhibiting the transfer of melanin bodies, and inhibiting the activity of various inflammatory factors.
Skin color is closely related to the amount of melanin in the epidermis, especially stains and dullness, most of which are caused by melanin deposition. Melanin is produced by melanocytes at the base of the epidermis and is transferred to keratinocytes through melanocyte dendrites. Melanin transferred to keratinocytes is deposited in the epidermal cells, resulting in dull, dull, and pigmented skin. Nicotinamide can block the melanin body for transport, so that the melanin body can not spread to the surrounding cells, to achieve the effect of whitening spots.
Nicotinamide promotes the metabolism of aging cuticles, and the melanin in cuticles is excreted with the metabolism of aging cuticles, to achieve the effect of whitening spots.
The formation of melanin is affected by inflammatory factors, various hormones in the body, intracellular matrix, ultraviolet, and other factors. These influencing factors form a large number of various factors through stimulating the body tissues to stimulate melanocytes to produce melanin. Before inflammatory factors stimulate melanocytes to start the melanin production mechanism, nicotinamide can inhibit its activity, blocking the front end of melanin formation, to achieve the effect of whitening spots.
