Which methods can produce 3, 5-dihydroxypentyl benzene?

There are several methods that can produce 3, 5-dihydroxypentyl benzene.Here are three possible approaches:

Synthesis from 3-hydroxypent-4-yne:

One way to produce 33, 5-dihydroxypentyl benzene is to start with 3-hydroxypent-4-yne and then use a dehydration reaction to remove a molecule of water and form the alkyne.The alkyne can then be reduced using a suitable reducing agent to produce 3, 5-dihydroxypentyl benzene.

In this reaction sequence, 3-hydroxypent-4-yne is treated with trifluoroacetic acid (TFA) to remove a molecule of water and form the alkyne.The alkyne is then reduced using lithium aluminum hydride (LiAlH4) to produce 3, 5-dihydroxypentyl benzene.

Synthesis from 3,5-dihydroxypentan-2-one:

Another way to produce 3, 5-dihydroxypentyl benzene is to start with 3,5-dihydroxypentan-2-one and then use a decarboxylation reaction to remove a molecule of carbon dioxide and form the alkyne.The alkyne can then be reduced using a suitable reducing agent to produce 3, 5-dihydroxypentyl benzene.

In this reaction sequence, 3,5-dihydroxypentan-2-one is treated with potassium hydroxide (KOH) to remove a molecule of carbon dioxide and form the alkyne.The alkyne is then reduced using lithium aluminum hydride (LiAlH4) to produce 3, 5-dihydroxypentyl benzene.

Synthesis from 3-bromo-5-hydroxypent-1-yne:

A third way to produce 3, 5-dihydroxypentyl benzene is to start with 3-bromo-5-hydroxypent-1-yne and then use a dehalogenation reaction to remove the bromine atom and form the alkyne.The alkyne can then be reduced using a suitable reducing agent to produce 3, 5-dihydroxypentyl benzene.

In this reaction sequence, 3-bromo-5-hydroxypent-1-yne is treated with sodium iodide (NaI) in acetone to remove the bromine atom and form the alkyne.The alkyne is then reduced using lithium aluminum hydride (LiAlH4) to produce 3, 5-dihydroxypentyl benzene.

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