25-Hydroxy Calcifediol, also known as 25-OH-D3, is the main form of vitamin D, which is synthesized by the skin following exposure to ultraviolet light, and in small amounts, through foods and other supplements. The levels of vitamin D in our bodies are usually determined by measurements of the 25-hydroxy calcifediol. Due to the stable nature of the 25-hydroxy Calcifediol, which are not directly affected by diet and lifestyle, the levels in the blood are high, The half-decline cycle is long, usually two to three weeks, so the storage of vitamin D is determined using the levels of 25-hydroxy Calcifediol in the blood.
25-hydroxy, Calcifediol is converted by the hydroxylation of vitamin D in the liver, which is converted by the kidneys into the active 1, 25-dihydroxy vitamin D, the main active form of vitamin D, which may be affected by abnormalities in the liver or kidneys.
